Premature Ejaculation

The recommended dose is 30 mg, which may be increased to 60mg.

Only take the medicine 1 to 3 hours before sexual activity is anticipated.

Do not take this medicine more than once every 24 hours or every day.

Swallow the tablets whole to avoid a bitter taste, with at least one full glass of water. This may help lower your chance of fainting.

This medicine can be taken with or without food.

This medicine should not be used by men under 18 or over 65 years of age.

Discuss your Priligy treatment with your doctor after the first 4 weeks or after 6 doses to see whether you should continue treatment. If treatment is continued, you should see your doctor again to discuss this at least every six months.

• Allergy to dapoxetine or any of the other ingredients of this medicine

• Heart problems, such as heart failure or problems with the heart rhythm

• A history of fainting

• A history of mania (symptoms include feeling over−excited, irritable or not being able to think clearly) or severe depression

• A history of moderate or severe liver problems.

• Currently taking the following medicines:

   o Medicines for depression called ‘monoamine oxidase inhibitors’ (MAOIs)

   o Thioridazine used for schizophrenia

   o Other medicines for depression

   o Lithium − a medicine for bipolar disorder

   o Linezolid − an antibiotic used to treat infections o Tryptophan − a medicine to help you sleep

   o St John’s wort − a herbal medicine

   o Tramadol − used to treat serious pain

   o Medicines used to treat migraines.

Stop taking Priligy and see your doctor straight away if:

• You have fits (seizures)

• You faint or feel light headed when you stand up

• You notice any changes in your mood

• You have any thoughts of suicide or harming yourself. If you notice any of the above, stop taking this medicine and see your doctor straight away.

Fainting and low blood pressure

This medicine can make you faint or make your blood pressure drop when you stand up. To help lower the chance of this happening:

• Take this medicine with at least one full glass of water.

• Do not take this medicine if you are dehydrated (you do not have enough water in your body). This can happen if:

- You have not had anything to drink in the past 4 to 6 hours

- You have been sweating for a long time

- You have an illness where you have a high temperature, diarrhoea or being sick.

• If you feel like you might faint (such as feeling sick, feeling dizzy, light headed, confused, sweaty or an abnormal heart beat), or feel light headed when you stand up, immediately lie down so your head is lower than the rest of your body or sit down with your head between your knees until you feel better. This will stop you from falling and hurting yourself if you do faint. • Do not stand up quickly after you have been sitting or lying down for a long time. • Do not drive or use any tools or machines if you feel faint when taking this medicine. • Tell your doctor if you faint when taking this medicine.

Very common side effects (more than 1 in 10 men):

• Feeling dizzy

• Headache

• Feeling sick

Common side effects (up to 1 in 10 men):

• Feeling irritable, anxious, agitated or restless

• Feeling numb or having ‘pins and needles’

• Difficulty getting or keeping an erection

• Sweating more than normal or flushing

• Diarrhoea, constipation or having wind

• Stomach pain, bloating or being sick

• Problems sleeping or strange dreams

• Feeling tired or sleepy, yawning

• Blocked nose (nasal congestion)

• A rise in blood pressure

• Difficulty concentrating

• Shaking or trembling

• Lower interest in sex

• Ringing in the ears

• Blurred vision

• Indigestion 6 • Dry mouth

Uncommon side effects (up to 1 in 100 men):

• Fainting or feeling dizzy upon standing (see advice above)

• Change in mood, feeling overly excited or feelings of paranoia

• Feeling confused, disoriented or unable to think clearly

• Slow or irregular heartbeat or increase in heart rate

• Loss of sex drive, problems reaching orgasm

• Feeling weak, sedated, lethargic or fatigued

• Feeling depressed, nervous or indifferent

• Feeling hot, jittery, abnormal or drunk

• Vision problems, eye pain or dilated pupils

• Low or high blood pressure

• Feeling itchy or cold sweat

• Spinning sensation

• Abnormal taste

• Teeth grinding

Rare side effects (up to 1 in 1,000 men):

• Feeling dizzy following exertion

• Sudden onset of sleep

• Urgency of bowel action.

• Emla Cream 

https://www.medicines.org.uk/emc/files/pil.1269.pdf