Erectile Dysfunction

Take a Vardenafil tablet about 25 to 60 minutes before sexual activity. With sexual stimulation you may achieve an erection anywhere from 25 minutes up to four to five hours after taking Vardenafil.

Swallow one tablet with a glass of water.

Do not take Vardenafil more than once a day. 

Men who take too much Vardenafil may experience more side effects or may get severe back pain. 

• If you are allergic to avanafil or any of the other ingredients of this medicine

• If you are taking “nitrate” medicines for chest pain (angina), such as amyl nitrite or glyceryl trinitrate. Spedra can increase the effects of these medicines and severely lower your blood pressure

• If you are taking medicines for HIV or AIDS such as ritonavir, indinavir, saquinavir, nelfinavir or atazanavir

• If you are taking medicines for fungal infections such as ketoconazole, itraconazole or voriconazole or certain antibiotics for bacterial infections, such as clarithromycin or telithromycin

• If you have a serious cardiac problem

• If you have had a stroke or heart attack in the last 6 months

• If you have low blood pressure or high blood pressure not controlled by medicines

• If you have chest pain (angina) or you get chest pain during sexual intercourse

• If you have a serious liver or kidney problem

• If you have loss of vision in one eye due to not enough blood getting to your eye (non-arteritic ischemic optic neuropathy [NAION])

• If certain serious eye problems run in your family (such as retinitis pigmentosa).

• If you are taking riociguat. This medicine is used to treat pulmonary arterial hypertension (i.e., high blood pressure in the lungs) and chronic thromboembolic pulmonary hypertension (i.e., high blood pressure in the lungs secondary to blood clots). PDE5 inhibitors have been shown to increase the hypotensive effects of this medicine.

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Most of the effects are mild or moderate.

Partial, sudden, temporary or permanent decrease or loss of vision in one or both eyes has been experienced by patients. Stop taking Vardenafil and contact your doctor immediately.

Sudden decrease or loss of hearing has been reported.

Cases of sudden death, fast or altered heart beat, heart attack, chest pain, and trouble in cerebral circulation (including temporarily decreased blood flow to parts of the brain and bleeding in the brain) have been reported in men taking vardenafil. Most of the men who experienced these side effects had heart problems before taking this medicine. It is not possible to determine whether these events were directly related to vardenafil.

Very common (more than 1 in 10 users):

Headache

Common (up to 1 in 10 users):

Dizziness

Flushing

Blocked or runny nose

Indigestion

Uncommon (up to 1 in 100 users):

Swelling of skin and mucous tissue including swollen face, lips or throat

Sleep disorder

Numbness and impaired perception of touch

Sleepiness

Effects on vision; redness of the eye, effects on colour vision, eye pain and discomfort, light sensitivity

Ringing in the ears; vertigo

Fast heart beat or pounding heart

Breathlessness

Stuffy nose

Acid reflux, gastritis, abdominal pain, diarrhoea, vomiting; feeling sick (nausea), dry mouth

Raised levels of liver enzymes in your blood

Rash, reddened skin

Back or muscle pain; increase in blood of a muscle enzyme (creatine phosphokinase), muscle stiffness

Prolonged erections

Malaise

Rare (up to 1 in 1,000 users): 

Inflammation of the eyes (conjunctivitis)

Allergic reaction

Anxiety 

Fainting

Amnesia

Seizure

Increase pressure in the eye (glaucoma), lacrimation increased

Effects on the heart (such as heart attack, altered heart beat or angina)

High or low blood pressure

Nose bleed

Effect on results of blood tests to check liver function

Sensitivity of the skin to sun light

Painful erections

Chest pain

Temporarily decreased blood flow to parts of the brain

Very rare or not known (may affect less than 1 in 10,000 users or frequency cannot be estimated from the available data):

Blood in the urine (Haematuria)

Penile bleeding (Penile Haemorrhage)

Presence of blood in the semen (Haematospermia)

Sudden death; Bleeding in the brain

See other products under erectile dysfunction.

https://www.medicines.org.uk/emc/files/pil.9656.pdf