Antimalarial Treatment

Atovaquone and Proguanil

250mg/100mg Tablets

  • Generic for Malarone
  • Taken once daily
  • Continued for 7 days after travel
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£39.99

Atovaquone and Proguanil Medical Information

Atovaquone/Proguanil hydrochloride belongs to a group of medicines called antimalarials.

It contains two active substances, atovaquone and proguanil hydrochloride. Atovaquone/Proguanil hydrochloride is used to:

• Prevent malaria

• Treat malaria Malaria is spread by the bite of an infected mosquito, which passes the malaria parasite (Plasmodium falciparum) into the bloodstream.

Atovaquone/Proguanil hydrochloride prevents malaria by killing this parasite.

For people who are already infected with malaria, Atovaquone/Proguanil hydrochloride also kills these parasites.

As well as taking Atovaquone/Proguanil hydrochloride, it is very important that you also take steps to avoid being bitten by mosquitoes:

• Use insect repellent on exposed areas of the skin

• Wear light coloured clothing that covers most of the body, especially after sunset as this is the time when mosquitoes are most active

• Sleep in a screened room or under a mosquito net impregnated with insecticide

• Close windows and doors at sunset, if they are not screened

• Consider using an insecticide (mats, spray, plug-ins) to clear a room of insects or to deter mosquitoes from entering the room

• Start taking Atovaquone/Proguanil hydrochloride 1 to 2 days before travelling to an area which has malaria

• Continue taking it every day during your stay

• Continue taking it for another 7 days after your return to a malaria-free area

Allergy to atovaquone and/or proguanil hydrochloride or any of the ingredients of this medicine

Very common side effects (may affect more than 1 in 10 people):

• headache

• feeling sick and being sick (nausea and vomiting)

• stomach pain

• diarrhoea

Common side effects (may affect up to 1 in 10 people):

• dizziness

• sleeping problems (insomnia)

• strange dreams

• depression

• loss of appetite 5

• fever

• rash, which may be itchy

• cough

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