HRT - Oestrogen Only

You may put an Evorel patch on at any time if:

• You have not used HRT before your menopause and no longer have menstrual periods

• Your menstrual cycles are not regular and you are not pregnant

• You are changing from HRT that does not give you a withdrawal bleed

Put an Evorel patch on within 5 days of the start of bleeding if:

• You are not currently using HRT and still having regular periods

Put an Evorel patch on at the end of a treatment cycle or one week after you finish using another HRT product if:

• You are changing from an HRT medicine that gives you a withdrawal bleed If you are using another type of HRT:

• The day you start will depend on the type of HRT you have been using

• Talk to your doctor if you are not sure which type of HRT you are using

Using the patches

The patches need to be changed twice a week.

Start a new pack of Evorel as soon as you finish one. Do not leave a break between packs.

Changing your patches

• You must change the patches twice a week to give your body a steady supply of hormones. There is enough hormone in each patch to last for several days

• Change your patch on the same two days every week. This will mean that one patch is on for three days and the next patch for four days

• You have or have ever had breast cancer, or if you are suspected of having it

• You have cancer which is sensitive to oestrogens such as cancer of the womb lining (endometrium), or if you are suspected of having it

• You have any unexplained vaginal bleeding

• You have excessive thickening of the womb lining (endometrial hyperplasia) that is not being treated

• You have or have ever had a blood clot in a vein (thrombosis) such as in the legs (deep venous thrombosis) or the lungs (pulmonary embolism)

• You have a blood clotting disorder (such as protein C, protein S or antithrombin deficiency)

• You have or recently have had a disease caused by blood clots in the arteries, such as a heart attack, stroke or angina

• You have or have ever had a liver disease and your liver functiontests have not returned to normal

• You have a rare blood problem called “porphyria” which is passed down in families (inherited)

• You are allergic (hypersensitive) to estradiol or any of the other ingredients of Evorel

The following diseases are reported more often in women using HRT compared to women not using HRT:

• breast cancer;

• abnormal growth or cancer of the lining of the womb (endometrial hyperplasia or cancer);

• ovarian cancer;

• blood clots in the veins of the legs or lungs (venous thromboembolism);

• heart disease;

• stroke;

• probable memory loss if HRT is started over the age of 65.

Very common, may affect more than 1 in 10 people:

• Headache

• Skin reactions at the patch application site (including irritation, burning, rash, dryness, bleeding, bruising, inflammation, swelling, skin pigmentation, hives, and blisters)

• Breast tension and pain

• Menstrual pains

• Menstrual disorder.

Common, may affect up to 1 in 10 people:

• Depression

• Nervousness

• Mood changes

• Sleeplessness

• Nausea (feeling sick)

• Indigestion

• Diarrhoea

• Abdominal pain

• Bloated feeling

• Acne

• Rash

• Dry skin

• Itching

• Breast enlargement

• Heavy menstrual periods

• A white or yellowish discharge from the vagina

• Irregular vaginal bleeding

• Severe uterine contractions

• Inflammation of the vagina

• Abnormal growth of the womb lining (endometrial hyperplasia)

• Pain (e.g. back pain, arms, legs, wrists, ankles)

• Weakness

• Fluid retention (oedema) in the extremities (hands and feet)

• Weight changes.

See other oestrogen only HRT products 

https://www.medicines.org.uk/emc/files/pil.10931.pdf